Amelioration of cisplatin induced nephrotoxicity in Swiss albino mice by Rubia cordifolia extract (Record no. 30235)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01786pab a2200289 454500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150901b2008 xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | Tata Memorial Hospital |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | English |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | |
| Item number | |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Joy J |
| 245 ## - TITLE STATEMENT | |
| Title | Amelioration of cisplatin induced nephrotoxicity in Swiss albino mice by Rubia cordifolia extract |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Date of publication, distribution, etc. | 2008 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 111-115 |
| 490 ## - SERIES STATEMENT | |
| Series statement | |
| Volume/sequential designation | Vol 4 Issues 3 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Cisplatin is one of the most effective chemotherapeutics against a wide range of cancers including head, neck, ovarian and lung cancers. But its usefulness is limited by its toxicity to normal tissues, including cells of the kidney proximal tubule. The purpose of the present study is to investigate whether the hydro-alcoholic extract of Rubia cordifolia could decrease the intensity of toxicity in Swiss albino mice. Materials and Methods: Cisplatin at a dose of 12 mg/kg body wt was administered intraperitoneally to Swiss albino mice. Another set of animals was given hydro-alcoholic extract of Rubia cordifolia at different doses along with cisplatin treatment. The antioxidant levels, serum creatinine, serum urea etc. were analyzed. Results: The extract could significantly decrease the cisplatin induced nephrotoxicity as inferred from the tissue antioxidant status in the drug administered animals. Remarkable change was observed in serum creatinine and urea levels. Lipid peroxidation in the kidney |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Rubia cordifolia, |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | nephrotoxiciity |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cisplatin |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Antioxidants |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | ckknair@yahoo.com |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nair CK |
| 773 ## - HOST ITEM ENTRY | |
| Host Biblionumber | 78381 |
| Main entry heading | Journal of Cancer Research and Therapeutics |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) | |
| a | Jul-Sep |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) | |
| a | India |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) | |
| a | Original Article |
| Withdrawn status | Lost status | Damaged status | Not for loan | Permanent Location | Current Location | Date acquired | Cost, normal purchase price | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tata Memorial Hospital | Tata Memorial Hospital | 2008-10-15 | 0.00 | AR8592 | 2015-09-02 | 2015-09-02 | Articles |