| 000 -LEADER |
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| fixed length control field |
01787pab a2200301 454500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
161010b2016 xxu||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Patil VM |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Preoperative Chemotherapy and Metronomic Scheduling of Chemotherapy in Locally Advanced Oral Cancers |
| Remainder of title |
|
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
New York |
| Name of publisher, distributor, etc. |
S. Karger |
| Date of publication, distribution, etc. |
2016 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
35-40 |
| 490 ## - SERIES STATEMENT |
|---|
| Series statement |
Vol. ,no. 91 Suppl 1 |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Locally advanced oral cavity cancers are treated with a multi-modality approach. Surgery is the most efficient local modality in comparison to chemoradiation in oral cancers. Preoperative chemotherapy has failed its expectations to improve disease-free survival or overall survival in resectable oral cancers. Its use as an organ preservation tool is being studied. Induction chemotherapy followed by assessment for surgery is an appropriate option for borderline resectable or technically unresectable oral cancer. Metronomic chemotherapy is being studied as a bridge to surgery and as adjuvant chemotherapy in locally advanced oral cancers. The role of induction chemotherapy in unresectable oral cancers is unproven. Metronomic chemotherapy has shown improved progression-free survival and overall survival in oral cancers in comparison to intravenous cisplatin. A phase 3 study for confirmation of this finding has begun. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Location of event |
Oral Cancers |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Location of event |
Chemotherapy |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Prabhash K |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Muddu V |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Banavali SD |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Joshi A |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Noronha V |
| 773 ## - HOST ITEM ENTRY |
|---|
| Main entry heading |
Oncology |
| Place, publisher, and date of publication |
New York : S. Karger |
| International Standard Serial Number |
1423-0232 |
| Related parts |
Vol.91 Suppl 1, no., p.35-40 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://10.3.0.2/mm01/Articles/AR17949.pdf |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
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| h |
TMH |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
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| b |
TMC |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
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| a |
Medical Oncology |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
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| c |
27463093 |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
|---|
| f |
International |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
|---|
| e |
journalArticle |
