343 PQTWiST analysis to compare the benefit of metronomic chemotherapy versus intravenous cisplatin for patients with head and neck cancer (Record no. 82641)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01679nab a22002777a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180109b2018 xxu||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Parthiban SK |
| Relator term | Corresponding author |
| 245 ## - TITLE STATEMENT | |
| Title | 343 PQTWiST analysis to compare the benefit of metronomic chemotherapy versus intravenous cisplatin for patients with head and neck cancer |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Date of publication, distribution, etc | 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Background: In an open label, Phase 2 randomised study, metronomic chemotherapy was found to be superior to intravenous cisplatin in terms of progression free survival in patients with Head and neck cancer. In this analysis we will assess the benefit of metronomic over intravenous cisplatin using quality adjusted time without symptom or toxicity analysis method. Methods: The overall survival in each arm will be partitioned into 3 health states. TOX state (Time spent in grade 3 or above toxicity after randomization and before progression), TWiST state (Time spent after randomization before progression without grade 3 or above toxicity) and REL state (Time spent after progression). The mean QTWiST was calculated for each arm using threshold utility analysis. The difference in QTWiST and the 95% CI of difference... |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Head and neck cancer |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Chemotherapy |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cisplatin |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Metronomic |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Noronha V |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | A Joshi |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | V Patil |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | S Dhumal |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | A Chandrashekar |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | N Pande |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | K Prabhash |
| 773 ## - HOST ITEM ENTRY | |
| Main entry heading | Annals of Oncology |
| Place, publisher, and date of publication | London : Oxford University Press, 2017 |
| Relationship information | Vol. 28 no.(supp_10), p. |
| International Standard Serial Number | 0923-7534 |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) | |
| Dept | Medical Oncology |
| Corporate name | TMC |
| Article Type | Research Article |
| Country type | International |
| Added Entry | TMH |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Item type | Articles |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent location | Current location | Date acquired | Barcode | Date last seen | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|
| Tata Memorial Hospital | Tata Memorial Hospital | 2018-01-09 | AR18734 | 2018-01-09 | Articles |