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Combination of classical and interphase cytogenetics to investigate the biology of myleoid disorders: detection of masked monosomy 7 in AML

In Leukemia Research
By: Kadam, P.
Contributor(s): Umerani A | Srivastava A | Masterson, M | Raza, A | Lampkin, B | .
Material type: materialTypeLabelArticleSeries: Vol 17 Issues 4.Publisher: 1993Description: 365-374.Subject(s): LeukemiaDDC classification: 616.155 In: Leukemia ResearchSummary: The authors conclude that FISH constitues a highly sophisticated molecular technique which can be extremely useful in select cases for detecting 'masked monosomy 7' as well as helping to determine the lineage of terminally mature cells in AML, thereby providing a handle on the effects of cytokines or chemotherapy on normal vs leukemic clones.
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The authors conclude that FISH constitues a highly sophisticated molecular technique which can be extremely useful in select cases for detecting 'masked monosomy 7' as well as helping to determine the lineage of terminally mature cells in AML, thereby providing a handle on the effects of cytokines or chemotherapy on normal vs leukemic clones.

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