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HLA diversity in four selected Gujarathi speaking caste groups from Western India. (Abstract No.p37.8 (C1))

In Tissue Antigens
By: Shankar Kumar, U.
Contributor(s): Chhaya, S | .
Material type: materialTypeLabelArticleSeries: Vol 59 Issues 2.Publisher: 2002Description: 133.Subject(s): HLA diversity | HematologyDDC classification: 616.15 In: Tissue AntigensSummary: Earlier studies using common genetic marker including HLA has indicated unique heterogeneity among the allelic frequencies in native Indian population which may be due to "Founder effect" rather than isolation dependent divergence. In this study using standard NIH two-stage Microlymphocytotoxicity assay we have determined HLA alleles on four Gujarathi speaking caste groups Viz. Bhramins, Lohanas, Banyas and Patels. These four caste groups practice strict endogamy. A cosideraqble difference in phenotype frequencies was observed among these caste groups studied. The HLA all
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Articles Articles Tata Memorial Hospital
616.15 suppl Available AR4606

Earlier studies using common genetic marker including HLA has indicated unique heterogeneity among the allelic frequencies in native Indian population which may be due to "Founder effect" rather than isolation dependent divergence. In this study using standard NIH two-stage Microlymphocytotoxicity assay we have determined HLA alleles on four Gujarathi speaking caste groups Viz. Bhramins, Lohanas, Banyas and Patels. These four caste groups practice strict endogamy. A cosideraqble difference in phenotype frequencies was observed among these caste groups studied. The HLA all

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