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Myeloid metaplasia in Aspirates from Englarged spleens : a clue in the absence of peripheral blood findings characteristic of myelofibrosis

In Acta Cytologica
By: sen, Rajeev.
Contributor(s): Mehta, Kamna | Gupta M | Singh S | Sen, Jyotsna | Sachadeva B | Singh H | Bhadani PP | .
Material type: materialTypeLabelArticleSeries: Vol 50 Issues 4.Publisher: 2006Description: 379-383.Subject(s): Spleens, myeloid metaplasis | DDC classification: In: Acta CytologicaSummary: Malakoplakia is a rare pseudotumoral inflammatory disease known to affect immunocompromised subjects. We report a 4-year-old boy with malakoplakia of colon who was diagnosed with celiac disease in late infancy; despite aggressive nutritional and medical management for celiac disease, symptoms did not resolve. His nitro-blue-tetrazolium test was compatible with chronic granulomatous disease. In colonic biopsy Michaelis-Gutmann bodies were seen.
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Malakoplakia is a rare pseudotumoral inflammatory disease known to affect immunocompromised subjects. We report a 4-year-old boy with malakoplakia of colon who was diagnosed with celiac disease in late infancy; despite aggressive nutritional and medical management for celiac disease, symptoms did not resolve. His nitro-blue-tetrazolium test was compatible with chronic granulomatous disease. In colonic biopsy Michaelis-Gutmann bodies were seen.

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