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A retrospective study of prognostic factors and outcome of oral adenoid cystic carcinoma

In Oral Oncology
Contributor(s): DCruz AK | Pai P | Chaturvedi P | Dinshaw KA | Lashkar S | Gupta T | Jain S | | Agarwal JP.
Material type: materialTypeLabelArticleSeries: Vol 2 Issues 1.Publisher: 2007Description: 217-218.Subject(s): Outcome | Adenoid cystic carcinoma | Salivary gland neoplasm | Oral cavity | DDC classification: In: Oral OncologySummary: Introduction: Adenoid cystic carcinoma (ACC) of head and neck region are uncommon malignancies and are characterized by slow evolution, protracted clinical course, multiple recurrences, and late distant metastasis. Methods and Materials: Between 1992 to 2004, 76 patients of ACC of oral cavity and oropharynx were studied retrospectively, using AJCC criteria 1997 with a median follow-up of 20 months (range, 1 137 mo). Our objective is to document the control rates, patterns of failure, survival statistics; and to define prognostic variables for treatment outcome. The median age at diagnosis was 44 years (11 72 years) with an equal sex distribution. Sixty-five (85.5%) patients treated were of advanced T-stage (T3 4). Perineural invasion (PNI), margin positivity and node positivity were present in 31.6%, 23.7%, and 21.1% patients respectively. Twenty-eight (39.5%) patients were treated with surgery alone, and 48 (57.9%) patients with surgical resection plus adjuvant radiotherapy. Using RT techniques appropri
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Articles Articles Tata Memorial Hospital
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Introduction: Adenoid cystic carcinoma (ACC) of head and
neck region are uncommon malignancies and are characterized by slow evolution, protracted clinical course, multiple recurrences, and late distant metastasis.
Methods and Materials: Between 1992 to 2004, 76 patients of
ACC of oral cavity and oropharynx were studied retrospectively, using AJCC criteria 1997 with a median follow-up of 20 months (range, 1 137 mo). Our objective is to document the control rates, patterns of failure, survival statistics; and to define prognostic variables for treatment outcome. The median age at diagnosis was 44 years (11 72 years) with an equal sex distribution. Sixty-five (85.5%) patients treated were of advanced T-stage (T3 4). Perineural invasion (PNI), margin positivity and node positivity were present in 31.6%, 23.7%, and 21.1% patients respectively. Twenty-eight (39.5%) patients were treated with surgery alone, and 48 (57.9%) patients with surgical resection plus adjuvant radiotherapy. Using RT techniques appropri

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