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Chronic myelomonocytic leukaemia (an analysis of fourteen consecutive cases)

In Journal of Association of Physicians of India
By: Athale UA.
Contributor(s): Advani SH | Kadam P | Nair CN | Iyer R | Nair R | .
Material type: materialTypeLabelArticleSeries: Vol 39 Issues 5.Publisher: 1991Description: 390-393.Subject(s): Indian | DDC classification: In: Journal of Association of Physicians of IndiaSummary: BV 9913 Fourteen consecutive cases of chronic myelomonocytic leukaemia aged 6 to 73 (mean 40.5) years were reviewed to define the natural history of the disease and the risk of acute transformation. The common presenting features included anaemia, fever, purpura, and bleeding tendencies. Abnormal karyotypes were seen in 4 of 6 patients subjected to cytogenetic analysis. Low dose cytosine arabinoside achieved complete remission in two and partial remission in one, of the four patients treated with this modality. The mean survival was 5.6 (range 2-12) months and two patients) evolved to acute myeloid leukaemia. The long term survival with the present form of therapy in chronic myelomonocytic leukaemia is poor
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Articles Articles Tata Memorial Hospital
(Browse shelf) Available AR3884

BV 9913 Fourteen consecutive cases of chronic myelomonocytic leukaemia aged 6 to 73 (mean 40.5) years were reviewed to define the natural history of the disease and the risk of acute transformation. The common presenting features included anaemia, fever, purpura, and bleeding tendencies. Abnormal karyotypes were seen in 4 of 6 patients subjected to cytogenetic analysis. Low dose cytosine arabinoside achieved complete remission in two and partial remission in one, of the four patients treated with this modality. The mean survival was 5.6 (range 2-12) months and two patients) evolved to acute myeloid leukaemia. The long term survival with the present form of therapy in chronic myelomonocytic leukaemia is poor

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