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Adaptive radiation therapy for pediatric head and neck malignancies: dosimetric implications

In Practical Radiation Oncology
Contributor(s): Chaudhari S | Tike P | Vora T | Khanna N | Mallik S | Pandit P | | Laskar S.
Material type: materialTypeLabelArticleSeries: Issues.Publisher: 2014Subject(s): DDC classification: In: Practical Radiation OncologySummary: Purpose This study was designed to evaluate the role of adaptive radiation therapy for children receiving curative radiation therapy to the head and neck region. Methods and materials Ten children receiving definitive, conformal radiation therapy to the head and neck region were prospectively evaluated for anatomic changes during the course of radiation therapy. Images were acquired midway through the number of planned radiation therapy fractions during the planned course of radiation therapy. Body contours, target volumes, and organs at risk were redrawn on the new set of images. Two sets of additional treatment plans were generated: (1) a nonoptimized plan (plan 2), that is, an overlay of the original plan (plan 1) on the new set of contours, and (2) an optimized plan (plan 3) with the new set of contours. These 3 sets of plans were then compared for dosimetric differences. Results Five children had nasopharynx carcinoma, whereas the other 5 had embryonal rhabdomyosarcoma. The average reduction i
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Purpose
This study was designed to evaluate the role of adaptive radiation therapy for children receiving curative radiation therapy to the head and neck region.

Methods and materials
Ten children receiving definitive, conformal radiation therapy to the head and neck region were prospectively evaluated for anatomic changes during the course of radiation therapy. Images were acquired midway through the number of planned radiation therapy fractions during the planned course of radiation therapy. Body contours, target volumes, and organs at risk were redrawn on the new set of images. Two sets of additional treatment plans were generated: (1) a nonoptimized plan (plan 2), that is, an overlay of the original plan (plan 1) on the new set of contours, and (2) an optimized plan (plan 3) with the new set of contours. These 3 sets of plans were then compared for dosimetric differences.

Results
Five children had nasopharynx carcinoma, whereas the other 5 had embryonal rhabdomyosarcoma. The average reduction i

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