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Blood Transfusion in the Critically Ill Patient

In Bangladesh Critical Care Journal
By: George JP.
Contributor(s): Myatra SN [Corresponding author].
Material type: materialTypeLabelArticlePublisher: 2018Description: .Subject(s): Anaemia in ICU | Transfusion Threshold | Transfusion Trigger | Packed Red Blood Cell Transfusion | Bleeding in ICU In: Bangladesh Critical Care Journal Vol. 6, no. 1, p. 40-46Summary: Abstract Anaemia is commonly seen in the intensive care unit and is a cause of increased morbidity in the critically ill patients. Blood transfusion seems to be the physiological solution for anaemia, however it is not without complications and associated risks, questioning the benefit of packed red blood cell transfusion in this population. Physiological thresholds for transfusion seem to be an interesting concept, but currently lack evidence. The transfusion trigger across most populations favours a restrictive strategy for packed red blood cell transfusion, with the exception of some subgroups. Despite the presence of storage lesions in old blood, evidence suggest that the freshest available blood, does not fare better than the oldest available blood from the blood bank. This article is a review of the current evidence with blood transfusion practices in the critically ill patients.
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Articles Articles Tata Memorial Hospital
Available AR18963

Address for Corresponding Author: sheila150@hotmail.com

Abstract
Anaemia is commonly seen in the intensive care unit and is a cause of increased morbidity in the critically ill patients.
Blood transfusion seems to be the physiological solution for anaemia, however it is not without complications and
associated risks, questioning the benefit of packed red blood cell transfusion in this population. Physiological
thresholds for transfusion seem to be an interesting concept, but currently lack evidence. The transfusion trigger across
most populations favours a restrictive strategy for packed red blood cell transfusion, with the exception of some
subgroups. Despite the presence of storage lesions in old blood, evidence suggest that the freshest available blood, does
not fare better than the oldest available blood from the blood bank. This article is a review of the current evidence with
blood transfusion practices in the critically ill patients.

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