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Adjuvant Therapy in Endometrial Cancer with Special Emphasis and Reference to Indian Setting

In Indian Journal of Gynecologic Oncology
By: Gurram L.
Contributor(s): Mahantshetty U [Corresponding Author] | Chopra S | Gupta S | Ghosh J | Gulia S | Maheshwari A | Shylasree TS.
Material type: materialTypeLabelArticlePublisher: 2019Description: .Subject(s): Endometrial cancer | Adjuvant therapy | Radiation therapy | Chemotherapy In: Indian Journal of Gynecologic Oncology [Epub ahead of print]Summary: The incidence of endometrial cancer (EC) is on the rise in India. The median age at presentation is lesser than the Western population. Majority of the patients present in early stages with excellent overall survival rates after surgery. Adjuvant therapy is essential in high-risk stages I–III for improving outcomes. The quality and extent of surgery, and complete histopathological information are important factors for outcome and tailoring adjuvant therapy. Depending on patients and histopathological factors, various risk groups have been defined for prognostication and defining adjuvant therapy. Adjuvant therapy including external radiation, vaginal brachytherapy, chemotherapy and combined chemoradiotherapy has been tried depending on various risk groups. The purpose of this article is to review and interpret and update the results of existing literature on adjuvant therapy in EC with a special focus on Indian reports and standards.
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Articles Articles Tata Memorial Hospital
Available AR19772

Address for Corresponding Author: mahantshettyum@tmc.gov.in

The incidence of endometrial cancer (EC) is on the rise in India. The median age at presentation is lesser than the Western population. Majority of the patients present in early stages with excellent overall survival rates after surgery. Adjuvant therapy is essential in high-risk stages I–III for improving outcomes. The quality and extent of surgery, and complete histopathological information are important factors for outcome and tailoring adjuvant therapy. Depending on patients and histopathological factors, various risk groups have been defined for prognostication and defining adjuvant therapy. Adjuvant therapy including external radiation, vaginal brachytherapy, chemotherapy and combined chemoradiotherapy has been tried depending on various risk groups. The purpose of this article is to review and interpret and update the results of existing literature on adjuvant therapy in EC with a special focus on Indian reports and standards.

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